Those who monitor blood sugar spikes tend to be aware of the properties of certain foods that help regulate blood sugar levels. Some supplements have this potential and, according to Dr. Wandyk Allison, the formula with “the most evidence” for controlling blood sugar is berberine. “There are more clinical studies in humans and an effect comparable to metformin in several studies,” he mentions.
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Holder of a postgraduate diploma in endocrinology and clinical nutrition, the specialist explains that this supplement is not “just another herbal medicine against diabetes”, but also “acts on multiple metabolic targets”: “It has an action on several points of metabolism at the same time”, guarantees the performance and longevity expert.
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Berberine is one of the supplements with the potential to act on glycemic control.
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Glucose is a type of simple sugar that circulates throughout the body and provides energy to cells.
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Maintaining high blood sugar levels impacts health and tends to contribute to the emergence of other diseases.
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Certain habits impair blood sugar control
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The doctor points out that berberine “activates the enzyme AMP-activated protein kinase (AMPK), considered a central regulator of energy metabolism.” He specifies: “When AMPK is activated, the body increases the absorption of glucose by cells, particularly muscles. » According to Wandyk, this reduces the liver’s production of glucose, less gluconeogenesis – production from substances that are not carbohydrates.
Two other positive results of using the supplement are the improvement of insulin sensitivity and the stimulation of fats as an energy source, as the endocrinology graduate claims: “It is exactly this mechanism that resembles the effect of metformin, an oral medication used by patients to control type 2 diabetes.”
The supplement contains properties that promote blood sugar control
The specialist mentions that the supplement decreases the activity of pathways that produce glucose in the liver, such as phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase. He says the practical result is “less sugar released into the bloodstream throughout the day.”
Based on studies, Wandyk Allison mentions that the supplement changes the composition of the microbiota, favoring bacteria that produce more short-chain fatty acids, improving insulin sensitivity and reducing low-grade inflammation. “In other words, berberine also acts through the gut-metabolism axis,” he concludes.
Glucose is a type of simple sugar that circulates throughout the body and provides energy to cells.
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